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SECOND INTERNATIONAL SYMPOSIUM
ON THE ROLE OF SOY
IN PREVENTING AND TREATING CHRONIC DISEASE

September 15-18, 1996
Brussells, Belgium

SCIENTIFIC PROGRAM

Satellite Symposium

Current Understanding of Soy and Infant Health

A review of soy infant formula feeding
Fomon S and Ziegler E, University of Iowas, Iowa City, IA 52240

Soy-based infant formulas have been commercially available since the 1950s. Current commercial formulas contain methionine-fortified isolated soy protein as the protein source, corn syrup solids and/or sucrose as the carbohydrate and an improves mineral suspention system.


These formulas have been used for feeding infants with symptoms of cow's milk allergy and lactose intolerance, and have been useful as a refeeding regimen for onfants and children recovering from diarrhea. Because methionine-fertified soy-based formulas (SF) may be the sole source of nutrients during infancy, many growth studies have been conducted to assess the nutritionnal adequacy of thes formulas. In studies where they have been compered with human milk (HM) or cow's milk based formulas (MF), SF have supported similar growth and nutrient retention rates of term infants. Since the nutrient requirements of small pretern infants differ from that of term infants, the American Academy of Pediatrics does not recommend that soy formulas be fed to small pretern infants. In a recent review, Fomon and Ziegler (1992) summarize growth data of term infants exclusively formula-fed from 8 to 112 days of age. Gains in weight and lenght were similar between infants fed SF and infants MF. At similar energy intakes, 46 male infants and 55 females fed SF gained 31.4 <> 5,8 g/d and 28.3 <> 4,4 g/d from age 8 to 111 d respectively, and 57 male infants and 46 female infants fed MF gained 32.1 <>5,2 and 28,0 <> 5,6 g/d. Churella et al (1994) reported that SF containing 2,45 g protein / 100 kcal and approximately 640 Ùmol total sulfur-containing amino acids/100 kcal adequately met the protein needs of term infants from 2 to 112 days of age. Growth was similar to infants fed MF or HM cited in the literature. Results of studies by Venkataraman et al, 1992 and Mimouni et al, 1993 indicate that the bone mineral content of infants fed SF is similar to that observed in infants fed HM of MF. Numerous clinical studies support the nutritional adequacy of SF.

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